A STUDY TO COMPARE CLINICAL OUTCOMES OF BARE METAL STENT AND ZOTAROLIMUS ELUTING STENT

Abstract

Coronary artery disease (CAD) is the leading cause of death and disability world over. To achieve PCI; either bare metal stent (BMS) or drug eluting stent (DES) are used. The objective of the present retrospective study was to compare the safety and efficacy between BMS (Driver ^TM) and DES (Endeavor ^TM) in patients who underwent coronary angioplasty. 218 patients underwent PCI between December 2007 and June 2009 at The Heart Care Clinic, Ahmedabad, out of which 109 patients were implanted with Zotarolimus Eluting Stent (ZES) and 109 were implanted with BMS. Both groups had similar demographics and risks factors. Follow-up was conducted at1 month, 6 month and 12 month. The end point was all-cause mortality and Major Adverse Cardiac Event (MACE). All cause death was reported similar in both groups (0.92%; p=0.478). Overall MACE rates were 26.60% in BMS group and 32.10% in DES group (p=0.458). Restenosis rate at one month was 0.92% Vs 1.83% p=0.998, at six month was 0.00% Vs 1.83% p=0.479 and at twelve month was 0.00% Vs 1.83% p=0.998 respectively in BMS and DES groups. Safety and efficacy study result demonstrated that MACE and mortality rate appears lower in BMS group compare to DES group however, was not significant statistically.