Drug Use Evaluation in the Pediatrics Admitted with Severe Respiratory Tract Infections

Vineela Chadalavada, Triveni P, Hameeda Begum Md, Pujitha S

Abstract

The objective of the present study is to evaluate drug prescribing patterns in children admitted with respiratory tract infections into pediatric ward. This is a prospective cross-sectional study conducted for a period of one year at a tertiary hospital located in a city of Andhra Pradesh, South India. The study was done by using prescribing indicators from the World health organization (WHO) manual for the conduction of drug use evaluation studies. The prevalence of respiratory tract infections, particularly lower respiratory tract infection is high among children less than 5 years. 54.39% of drugs are prescribed with brand names, of which the majority of drugs are administered through parenteral route (58.26%). Antibiotics (34.7%) are highly prescribed in all the cases followed by other category drugs. A significant difference was found in the evaluation of prescribed daily dose and standard dose. The profile of drug use in the present study was similar to previous Indian studies. Most of the prescribing encounters are parental forms and band names that need exploration of the present treatment trends. The present baseline data can serve for the development of national Pediatric prescribing guidelines in the future.

Full Text:

PDF

References

Pneumonia: The forgotten killer of children. 2006. The United Nations Children’s Fund (UNICEF)/World Health Organization (WHO). Available at: https://www.who.int/news-room/detail/. Assessed Dec 2019.

K Park. 2013.Epidemiology of acute respiratory infections. In: K Park (editor). Preventive and Social Medicine. Bhanot publishers. 157-163.

Adam L. Hersh, MD, PhD, Mary Anne Jackson, MD, Lauri A. Hicks, DO, and the committee on infectious diseases. Principles of Judicious Antibiotic Prescribing for Upper Respiratory Tract Infections in Pediatrics. American academy of pediatrics. 2013; 132:1146-1154.

More than 90% of the world’s children breathe toxic air every day. 2018. News release Geneva. Available at: https://www.who.int/news-room/detail/. Assessed Dec 2019.

Raosoft. Sample size calculator . Available at: http://www.raosoft.com/samplesize.html.

World Health Organization. How to investigate drug use in health facilities: Selected drug use indicators. Geneva, World Health Organization 1993. WHO/DAP 1993; 1: 1-87.

World Health Organization. 2010. WHO model formulary for children. Available from: https://apps.who.int/iris/handle/10665/44309.

World Health Organization. Model List of Essential Medicines 2019 Available from: https://apps.who.int.

WHO Collaborating Center for Drug Statistics Methodology 2019 Available from: https://www.whocc.no/atc_ddd_index/

ICH Harmonised Guideline Integrated Addendum To ICH E6(R1): Guideline For Good Clinical Practice ICH E6(R2) ICH Consensus Guideline: Available from: https://ichgcp.net.

Kokani VR, Pandit PR, Bhave KA. Antimicrobial prescribing pattern in the treatment

of acute respiratory tract infections in children in a tertiary care hospital. Int J Basic Clin Pharmacol., 2016; 5: 1770-4.

Gupta N, Jain SK, Ratnesh, Chawla U, Hossain S, Venkatesh S. An evaluation of diarrheal diseases and acute respiratory infections control programmes in a Delhi slum. Indian J Pediatr., 2007; 74:471–

Pajapti B, Talsania N, Sonaliya KN. A study on prevalence of acute respiratory tract infections (ARI) in under-five children in urban and rural communities of Ahmedabad district, Gujarat. Natl J Community Med., 2011; 2: 255–9.

Islam F, Sarma R, Debroy A, Kar S, Pal R. Profiling acute respiratory tract infections in children from Assam, India. J Global Infect Dis., 2013; 5: 8–14.

Sharma D, Kuppusamy K, Bhoorasamy A. Prevalence of acute respiratory infections and their determinants in under five children in urban and rural areas of Kancheepuram district, South India. Ann Trop Med Public Health, 2013; 6: 513-8.

Kumar SG. Prevalence of acute respiratory infection among under-five children in urban and rural areas of puducherry, India. J Nat Sci Biol Med., 2015 Jan-Jun;6(1):3-6. doi: 10.4103/0976-9668.149069.

K Shamshy, I. Mufida Begum, P. Perumal. Drug Utilization of Antimicrobial drug in Pediatrics Population in a tertiary care hospital in Erode, Tamilnadu,India. IJPRIF, 2011;3 : pp 1530-1536.

Andrade C, Rao TSS. Prescription writing: Generic or brand?. Indian J Psychiatry, 2017;59(2):133–137. doi:10.4103/psychiatry.IndianJPsychiatry_222_17.

Thiruthopu NS, Mateti UV, Bairi R, Sivva D, Martha S. Drug utilization pattern in South Indian pediatric population: A prospective study. Perspect Clin Res., 2014;5:178-83.

Tandon VR. Fatal adverse drug reactions: Experience of adverse drug reactions in a tertiary care teaching hospital of North India - A case series. Indian J Crit Care Med., 2014;18(5):315–319. doi:10.4103/0972-5229.132499.

Rekha MM, Mubeena T. A study on role of Doctor of Pharmacy in Drug Utilization Evaluation Pattern Analysis in inpatient units and reporting its co morbidities in a tertiary care teaching hospital. PharmaTutor, 2017; 5(10): 55-62.

Vineela Chadalavada et al. Drug utilization evaluation and assessment of economic burden of anticoagulants in a tertiary care hospital in South India. J Pharm Sci Innov., 2018;7:188-194. http://dx.doi.org/10.7897/2277-4572.075106 .

Refbacks

  • There are currently no refbacks.


Bookmark and Share