Study the Effect of Oxides Emitted from the Smoke of Bakeries on the Density of Bone

Abstract

Objectives: Osteoporosis is bone disorders that excess a person’s dangers of fracture due to low bone mineral density, impaired bone microarchitecture/mineralization, & diminution bone strength. This asymptomatic condition often remains undiagnosed until it manifests as a low-trauma fracture of the hip, spine, proximal   humerus, pelvis, & wrist, which frequently leads to hospitalization. Methods: The present study of 41 bakeries worker’s various places in Baghdad. Serum levels of vitamin D₃, PTH hormone, Calcium, magnesium   and phosphorus were measured and analyzed of the bakeries smoke resulting from the combustion of kerosene substance by a device (aeroqual).Results: a significant increase in serum level of parathyroid hormone in bakery workers' group when the compared to a healthy control group (P=0.003). a slightly decrease of vitamin D₃ in bakery worker groups as compared with a healthy control group, but it was not significant differences (p=0.068). Calcium, magnesium & phosphorus were determined in sera of healthy control group & bakery workers' group as It is clear that, there is no significant variation in the   calcium   & magnesium concentrations between control group and bakery workers' group (p=0.612), (p=0.748), respectively, while a significant decrease in the phosphorus concentrations, in bakery workers' group as compared to a healthy control group. This result showed that there was an appositive correlation between magnesium and years of work. Conclusion: It is possible to predict the risk of osteoporosis in bakeries bone by measuring levels of vitamin D₃, PTH and bone minerals (Ca, Mg, and phosphorus) in their sera, and measuring the toxic oxides concentrations (NO₂ and CO) emitted from the smoke of bakeries resulting from combustion of kerosene used as fuel.

Keywords: Osteoporosis; Vitamin 25 (OH) D₃, PTH hormone, Magnesium.