Anticancer Properties of Amniotic Membrane Epithelial Cells

Abstract

Cancer is one of the important causes of mortality worldwildly. Abundance ofunsuccessful therapeutic methods, their side effects and the high cost of treatments, have led scientific societies to search novel targeting treatments. Anticancer properties of amniotic epithelial cells were emphasis previously, so in this study will review the anticancer factors secreted from this cell. These releasing factors including TNF-α, TNF-β, TGF-β, GM-CSF, NTF3, CCL18, BDNF, GCP-2, IL 2, 4, 6, and 8 induced apoptosis process in a variety of cancer cells. In sum up, this kind of stem cell with anticancer molecule are appropriated to use directly in cell therapy of cancer or indirectly use condition medium.