Study of Some Immunological and Biochemical Parameters Related with Vitiligo Patients

Abstract

The current study aimed to determine the relationship between certain immunological and biochemical parameters with Vitiligo patients.  The results revealed that a significant decrease (P<0.05) in the concentration of  CD8 (ng/ml) and a significant decrease (P<0.01)  in concentration of hormone T4 (ng/dl) in patients compared to healthy group , whereas there was non- significant differences in the levels of  CXCL-10(pg/ml) and TSH(µIU/ml), but there were a significant difference (P<0.01) in  the concentrations of  T3 (ng/ml) and reactive oxygen species(ROS) (ng/ml). According to the gender the males of patients has shown a significant decrease (P <0.05) in the concentration of CD8 in comparison with males control group and a significant decrease (P <0.01) in the concentrations of T4 and TSH hormones, while the data noticed a significant increase (P <0.05) in the concentration of (CXCL-10) as well as a significant increase (P<0.01) in the concentrations of ROS and T3. The comparison between females of patients with control showed a significant decrease in the concentrations of CD8, CXCL-10, T4, and TSH, but there was a significant increase in concentrations of ROS and T3.

Keywords: Vitiligo, Immunological parameters, Hormones.